Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2014;67:436-41 - Vol. 67 Num.06 DOI: 10.1016/j.rec.2013.10.011

Epicardial Adipose Tissue Is Associated With Visceral Fat, Metabolic Syndrome, and Insulin Resistance in Menopausal Women

María J. Fernández Muñoz a, Lourdes Basurto Acevedo b,, Nydia Córdova Pérez b, Ana Laura Vázquez Martínez b, Nayive Tepach Gutiérrez b, Sara Vega García b, Alberto Rocha Cruz b, Alma Díaz Martínez b, Renata Saucedo García b, Arturo Zárate Treviño b, Eduardo Alberto González Escudero b, José Antonio Degollado Córdova c

a Servicio de Cardiología, Hospital de Especialidades, Centro Médico Nacional del Instituto Mexicano del Seguro Social, México DF, Mexico
b Unidad de Investigación Médica en Enfermedades Endocrinas, Centro Médico Nacional del Instituto Mexicano del Seguro Social, México DF, Mexico
c Servicio de Imagenología, Hospital de Especialidades, Centro Médico Nacional del Instituto Mexicano del Seguro Social, México DF, Mexico

Refers to

Epicardial Fat, Metabolic Dysregulation, and Cardiovascular Risk: Putting Things Together
Francisco López-Jiménez, Ondrej Sochor
Rev Esp Cardiol. 2014;67:425-7
Full text - PDF

Keywords

Menopause. Metabolic syndrome. Cardiovascular risk factors. Epicardium. Echocardiography.

Abstract

Introduction and objectives

Epicardial adipose tissue has been associated with several obesity-related parameters and with insulin resistance. Echocardiographic assessment of this tissue is an easy and reliable marker of cardiometabolic risk. However, there are insufficient studies on the relationship between epicardial fat and insulin resistance during the postmenopausal period, when cardiovascular risk increases in women. The objective of this study was to examine the association between epicardial adipose tissue and visceral adipose tissue, waist circumference, body mass index, and insulin resistance in postmenopausal women.

Methods

A cross sectional study was conducted in 34 postmenopausal women with and without metabolic syndrome. All participants underwent a transthoracic echocardiogram and body composition analysis.

Results

A positive correlation was observed between epicardial fat and visceral adipose tissue, body mass index, and waist circumference. The values of these correlations of epicardial fat thickness overlying the aorta-right ventricle were r = 0.505 (P < .003), r = 0.545 (P < .001), and r = 0.515 (P < .003), respectively. Epicardial adipose tissue was higher in postmenopausal women with metabolic syndrome than in those without this syndrome (mean [standard deviation], 544.2 [122.9] vs 363.6 [162.3] mm2; P = .03).

Conclusions

Epicardial fat thickness measured by echocardiography was associated with visceral adipose tissue and other obesity parameters. Epicardial adipose tissue was higher in postmenopausal women with metabolic syndrome. Therefore, echocardiographic assessment of epicardial fat may be a simple and reliable marker of cardiovascular risk in postmenopausal women.

1885-5857/© 2014 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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