Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2016;69:256-71 - Vol. 69 Num.03 DOI: 10.1016/j.rec.2015.07.030

Health-related Quality of Life of Patients With Chronic Systolic Heart Failure in Spain: Results of the VIDA-IC Study

Josep Comín-Colet a,b,c,, Manuel Anguita d, Francesc Formiga e, Luis Almenar f, María G. Crespo-Leiro g, Luis Manzano h, Javier Muñiz i, José Chaves j, Trinidad de Frutos j, Cristina Enjuanes a,b,c

a Programa de Insuficiencia Cardiaca, Servicio de Cardiología, Hospital del Mar, Barcelona, Spain
b Grupo de Investigación Biomédica en Enfermedades del Corazón, Programa de Investigación en Procesos Inflamatorios y Cardiovasculares, Instituto Hospital del Mar de Investigaciones Médicas (IMIM), Barcelona, Spain
c Departamento de Medicina, Universidad Autónoma de Barcelona, Barcelona, Spain
d Programa de Insuficiencia Cardiaca y Trasplante, Servicio de Cardiología, Hospital Universitario Reina Sofía, Córdoba, Spain
e Servicio de Medicina Interna, Hospital Universitario de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
f Unidad de Insuficiencia Cardiaca y Trasplante, Servicio de Cardiología, Hospital Universitario La Fe, Valencia, Spain
g Unidad de Insuficiencia Cardiaca Avanzada y Trasplante Cardiaco, Servicio de Cardiología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade da Coruña (UDC), A Coruña, Spain
h Unidad de Insuficiencia Cardiaca y Riesgo Vascular en el Anciano, Servicio de Medicina Interna, Hospital Universitario Ramón y Cajal, Madrid, Spain
i Instituto Universitario de Ciencias de la Salud, Instituto de Investigación Biomédica de A Coruña (INIBIC), Universidade da Coruña, A Coruña, Spain
j Departamento Médico de Pfizer S.L.U., Madrid, Spain

Keywords

Heart failure. Health-related quality of life. Specific and generic quality of life questionnaires. Real life or routine clinical practice.

Abstract

Introduction and objectives

Although heart failure negatively affects the health-related quality of life of Spanish patients there is little information on the clinical factors associated with this issue.

Methods

Cross-sectional multicenter study of health-related quality of life. A specific questionnaire (Kansas City Cardiomyopathy Questionnaire) and a generic questionnaire (EuroQoL-5D) were administered to 1037 consecutive outpatients with systolic heart failure.

Results

Most patients with poor quality of life had a worse prognosis and increased severity of heart failure. Mobility was more limited and rates of pain/discomfort and anxiety/depression were higher in the study patients than in the general population and patients with other chronic conditions. The scores on both questionnaires were very highly correlated (Pearson r = 0.815; P < .001). Multivariable linear regression showed that being older (standardized β = -0.2; P = .03), female (standardized β = -10.3; P < .001), having worse functional class (standardized β = -20.4; P < .001), a higher Charlson comorbidity index (standardized β = -1.2; P = .005), and recent hospitalization for heart failure (standardized β = 6.28; P = .006) were independent predictors of worse health-related quality of life.

Conclusions

Patients with heart failure have worse quality of life than the general Spanish population and patients with other chronic diseases. Female sex, being older, comorbidity, advanced symptoms, and recent hospitalization are determinant factors in health-related quality of life in these patients.

1885-5857/© 2016 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

Cookies
x
To improve our services and products, we use cookies (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here.
Cookies policy
x
To improve our services and products, we use cookies (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here.