Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2004;57:146-54 - Vol. 57 Num.02 DOI: 10.1016/S1885-5857(06)60103-5

Intervention Program to Improve Secondary Prevention of Myocardial Infarction. Results of the PRESENTE (Early Secondary Prevention) Study

José A de Velasco a, Juan Cosín b, Manuel de Oya c, Eduardo de Teresa d

a Servicio de Cardiología. Hospital General Universitario. Valencia.
b Centro de Investigación. Hospital Universitario La Fe. Valencia. España.
c Fundación Jiménez Díaz. Madrid. España.
d Hospital Clínico Universitario. Málaga. España.

Keywords

Myocardial infarction. Prevention. Drugs.

Abstract

Introduction and objectives. Secondary prevention measures for myocardial infarction are inadequate. In Spain, the earlier PREVESE studies provided preliminary data. The aim of this study was to document the results of a simple intervention program for secondary prevention, implemented during the hospital stay. Patients and methods. We included 4174 patients (mean age 63.7 years, 73% men) discharged from 110 hospitals after myocardial infarction. Lipid profile was determined during the first 24 h after admission, and before discharge patients and relatives were informed about the disease and its prevention, and were given printed informative materials. The patients were seen again 6 months later. Results. After 6 months, 82.9% of the patients were examined and 10% were lost to follow-up. Mean blood pressure, weight and body mass index of the sample were lower, and lifestyle variables had improved. At discharge 87% were prescribed statins, 59.4% beta blockers, 51.2% ACE inhibitors and angiotensin blockers, and 94.1% antiplatelet drugs. These prescriptions were still being used 6 months later. There were substantial improvements in lipid values. Conclusions. The implementation of a simple intervention program for patients with myocardial infarction and their relatives, and the determination of lipid levels within 24 hours of admission, improved the secondary prevention measures at discharge and during the 6-month follow-up period. Acceptance of the program among the patients was good.

1885-5857/© 2004 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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