Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2014;67:259-69 - Vol. 67 Num.04 DOI: 10.1016/j.rec.2013.07.014

Prevalence of Atrial Fibrillation in Spain. OFRECE Study Results

Juan José Gómez-Doblas a, Javier Muñiz b, Joaquín J. Alonso Martin c, Gustavo Rodríguez-Roca d, José Maria Lobos e, Paula Awamleh c, Gaietá Permanyer-Miralda f, Francisco Javier Chorro g, Manuel Anguita h, Eulalia Roig i, on behalf of the OFRECE study collaborators

a Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain
b Instituto Universitario de Ciencias de la Salud, Universidad de A Coruña, A Coruña, Spain
c Servicio de Cardiología, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain
d Centro de Salud La Puebla de Montalbán, Toledo, Spain
e Centro de Salud Jazmín, Madrid, Spain
f Servicio de Cardiología, Hospital Universitario Vall d’Hebron, Barcelona, Spain
g Servicio de Cardiología, Hospital Clínico Universitario de Valencia, Valencia, Spain
h Servicio de Cardiología, Hospital Reina Sofía, Córdoba, Spain
i Servicio de Cardiología, Hospital de Sant Pau, Barcelona, Spain

Refers to

New Data About Atrial Fibrillation, Comment to the OFRECE Study
Rafael Vidal-Pérez, Fernando Otero-Raviña, Manuel Otero-Mata, José Ramón González-Juanatey
Rev Esp Cardiol. 2014;67:499
Full text - PDF
First, Let's See Where We Stand. Then, Let's See How Far We Can or Want to Go
Julián Pérez-Villacastín
Rev Esp Cardiol. 2014;67:249-50
Full text - PDF

Keywords

Atrial fibrillation. Prevalence. Epidemiology.

Abstract

Introduction and objectives

Atrial fibrillation is associated with substantial morbidity and mortality and both its incidence and prevalence are high. Nevertheless, comprehensive data on this condition in Spain are lacking. The aim of this study was to estimate the prevalence of atrial fibrillation in Spain.

Methods

A cross-sectional study was conducted in the general Spanish population older than 40 years. Two-stage random sampling was used, in which first-stage units were primary care physicians randomly selected in every Spanish province and second-stage units were 20 randomly selected persons drawn from each participating physician's assigned population. The reported prevalence was standardized for the age and sex distribution of the Spanish population. The electrocardiogram recordings were read centrally.

Results

Overall, 8343 individuals were evaluated. The mean age was 59.2 years (95% confidence interval, 58.6-59.8 years), and 52.4% of the participants were female. The overall age-adjusted prevalence of atrial fibrillation was 4.4% (95% confidence interval, 3.8-5.1). Prevalence was similar in both sexes, men 4.4% (3.6-5.2) and women 4.5% (3.6-5.3), rising with increasing age older than 60 years. In patients older than 80 years, the prevalence was 17.7% (14.1-21.3). In 10% of patients an unknown atrial fibrillation was diagnosed.

Conclusions

The prevalence of atrial fibrillation in the general Spanish population older than 40 years is high, at 4.4%. The prevalence is similar in both sexes and rises steeply above 60 years of age. It is estimated that there are over 1 million patients with atrial fibrillation in the Spanish population, of whom over 90 000 are undiagnosed.

1885-5857/© 2014 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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