Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2011;64:579-86 - Vol. 64 Num.07 DOI: 10.1016/j.rec.2011.03.009

Prevalence of Metabolic Syndrome and its Components in Patients With Acute Coronary Syndrome

Ana Jover a, Emili Corbella b, Anna Muñoz c, Jesús Millán d, Xavier Pintó b, Alipio Mangas e, Manuel Zúñiga f, Juan Pedro-Botet g, Antonio Hernández-Mijares a,h,

a Servicio de Endocrinología, Hospital Universitario Dr. Peset y Fundación para la Investigación Hospital Universitario Dr. Peset, Valencia, Spain
b Unidad Funcional de Lípidos y Riesgo Cardiovascular, Servicio de Medicina Interna, Hospital Universitario de Bellvitge – Idibell, RETIC: RD06/0045/0007-PREDIMED, Barcelona, Spain
c Abbott Healthcare, Departamento Médico, Barcelona, Spain
d Unidad de Lípidos y Riesgo Vascular, Servicio de Medicina Interna, Hospital Universitario Gregorio Marañón, Madrid, Spain
e Unidad de Lípidos, Servicio de Medicina Interna, Hospital Universitario Puerta del Mar, Cádiz, Spain
f Unidad de Lípidos y Riesgo Vascular, Servicio de Medicina Interna, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
g Unidad de Lípidos y Riesgo Cardiovascular, Servicio de Medicina Interna, Hospital del Mar, Barcelona, Spain
h Departamento de Medicina, Universidad de Valencia, Valencia, Spain

Refers to

Metabolic Syndrome, Diabetes, and Coronary Artery Disease: a Very Common Association
José M. Vegas-Valle, José M. García-Ruiz, Ernesto Hernández-Martín, Jesús M. de la Hera
Rev Esp Cardiol. 2012;65:108-9
Full text - PDF

Keywords

Metabolic syndrome X. Coronary disease. High-density lipoproteins. Diabetes mellitus. Obesity.

Abstract

Introduction and objectives

A large proportion of patients with coronary disease have metabolic syndrome, although the frequency and association of its different components are not well understood. The aim of this study was to determine the prevalence of metabolic syndrome and the combination of its components in a Spanish cohort of patients with acute coronary syndrome.

Methods

Clinical histories of 574 inpatients with acute coronary syndrome in 6 tertiary hospitals were reviewed and the presence of metabolic syndrome and its components determined by applying Adult Treatment Panel III criteria. In a second step, the components of the metabolic syndrome were analyzed, excluding those patients with diabetes mellitus.

Results

The metabolic syndrome was present in 50.9% of patients and was more frequent in women than in men (66.3% vs. 47.3%; P<.001). The most prevalent component was carbohydrate metabolism disorder (85.3%), followed by low high-density lipoprotein cholesterol (HDLc) levels (80.5%). In nondiabetic patients, 34.6% had metabolic syndrome and the most prevalent component was low HDLc levels (86%), followed by high blood pressure and hypertriglyceridemia and, in fourth place, impaired fasting serum glucose levels.

Conclusions

The metabolic syndrome has a high prevalence in patients with an acute coronary syndrome, especially in women. The most frequent components are hyperglycemia and low HDLc levels. After excluding diabetic patients, the most prevalent diagnostic criterion of metabolic syndrome was low HDLc levels.

1885-5857/© 2011 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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