Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2012;65:29-37 - Vol. 65 Num.01 DOI: 10.1016/j.rec.2011.07.016

Validity for Use in Research on Vascular Diseases of the SIDIAP (Information System for the Development of Research in Primary Care): the EMMA Study

Rafel Ramos a,b,c,, Elisabet Balló a,d, Jaume Marrugat e, Roberto Elosua e,f, Joan Sala b,c,g, Maria Grau e, Joan Vila e,f, Bonaventura Bolíbar h, Maria García-Gil a,c, Ruth Martí a, Francesc Fina h, Eduardo Hermosilla h, Magdalena Rosell h, Miguel Angel Muñoz i, Daniel Prieto-Alhambra h, Miquel Quesada a,b,c

a Unidad de Investigación en Atención Primaria de Girona, IDIAP Jordi Gol, Institut Català de la Salut, Girona, Spain
b Instituto de Investigación Biomédica de Girona (IdIBGi), Girona, Spain
c Departamento de Ciencias Médicas, Facultad de Medicina, Universitat de Girona, Girona, Spain
d Programa de Doctorado en Salud Pública y Metodología de la Investigación Biomédica, Universitat Autònoma de Barcelona, Barcelona, Spain
e Grupo de Epidemiología y Genética Cardiovascular, Programa de Investigación en Procesos Inflamatorios y Cardiovasculares, IMIM, Barcelona, Spain
f CIBER de Epidemiología y Salud Pública, Barcelona, Spain
g Unidad Coronaria, Servicio de Cardiología, Hospital Josep Trueta, Institut Català de la Salut, Girona, Spain
h Institut d’Investigació en Atenció Primària, IDIAP Jordi Gol, Barcelona, Spain
i Unidad de Investigación en Atención Primaria de Barcelona, IDIAP Jordi Gol, Institut Català de la Salut, Barcelona, Spain

Keywords

Cardiovascular diseases. Risk factors. Validation studies. Databases.

Abstract

Introduction and objectives

Information in primary care databases can be useful in research, but the validity of these data needs to be evaluated. We sought to analyze the validity of the data used in the EMMA study based on data from the Information System for the Development of Research in Primary Care.

Methods

We compared the prevalence of cardiovascular risk factors observed in EMMA—hypertension, diabetes, hypercholesterolemia (and its treatments), obesity, and smoking—with equivalent data from the Registre Gironí del Cor (REGICOR), a population-based study that uses standardized methodology, in 2000. We also compared the incidence rates of vascular diseases and its association with these risk factors in a 5-year follow-up.

Results

We analyzed data from 34 823 participants included in EMMA and 2540 REGICOR2000 study participants aged 35 to 74. The prevalence of risk factors did not differ significantly between the 2 studies, except for the prevalence of former smokers in men, which was higher in REGICOR2000 (24.7% [95% confidence interval, 23.9%-25.5%] vs 30.1% [95% confidence interval, 27.1%-33.1%]), and the proportion of patients with lipid-lowering and antihypertensive therapy, which was higher in EMMA (46.9% vs 32.7% and 8.7% vs 6.3%, respectively). There were no differences between the 2 studies when comparing the incidence of vascular diseases (2.1% in both studies in men and 1.18% [95% confidence interval, 0.7%-1.7%] in REGICOR2000 vs 0.75% [95% confidence interval, 0.64%-0.87%] in EMMA in women) and its association with risk factors.

Conclusions

The prevalence of cardiovascular risk factors and their association with the incidence of vascular disease observed in the EMMA study are consistent with those observed in an epidemiological population-based study with a standardized methodology.

1885-5857/© 2012 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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