ISSN: 0300-8932 Factor de impacto 2023 7,2
Vol. 11. Núm. A.
Páginas 27-32 (Febrero 2011)

Administración upstream de inhibidores de la glucoproteína IIb/IIIa en el síndrome coronario agudo sin elevación del segmento ST: la estrategia TACTICS

Upstream Administration of Tirofiban in Non-ST-Elevation Acute Coronary Syndrome: The TACTICS Strategy

Manuel Piqué¿Isabel HernándezAntonio MiñanoFernando Worner Diz

Opciones

Resumen

El empleo de los inhibidores de la glucoproteína IIb/IIIa en el contexto del síndrome coronario agudo sin elevación del segmento ST es un tema muy controvertido. A pesar de la oposición a su uso en las últimas guías de revascularización de la Sociedad Europea de Cardiología, los autores seguimos defendiendo el beneficio de la estrategia utilizada en el ensayo clínico TACTICS: actitud intervencionista facilitada con tirofibán en los pacientes con riesgo moderado y alto. Argumentamos esta defensa basándonos en que consideramos que el tirofibán es superior a los otros inhibidores de la glucoproteína IIb/IIIa en estos pacientes, unido a las dudas que todavía nos plantea la bivalirudina y al convencimiento de que los nuevos antiagregantes no deben considerarse sustitutivos, sino complementarios.

Palabras clave

Síndromes coronarios agudos
Antiagregación plaquetaria
Protocolos clínicos
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