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Vol. 7. Núm. D.
Novedades en la reducción de la frecuencia cardiaca
Páginas 19D-25D (Junio 2007)
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Vol. 7. Núm. D.
Novedades en la reducción de la frecuencia cardiaca
Páginas 19D-25D (Junio 2007)
Novedades en la reducción de la frecuencia cardiaca
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Fisiopatología del miocardio isquémico. Importancia de la frecuencia cardiaca
The Pathophysiology of Myocardial Ischemia. The Importance of Heart Rate
José Moreu-Burgosa,
Autor para correspondencia

Correspondencia. Dr. J. Moreu-Burgos. Servicio de Cardiología. Sección de Hemodinámica. Hospital Clínico San Carlos. Prof. Martín Lagos, s/n. 28040 Madrid. España.
, Carlos Macaya-Miguelb
a Servicio de Cardiología. Sección de Hemodinámica. Hospital Virgen de la Salud. Toledo. España
b Servicio de Cardiología. Sección de Hemodinámica. Hospital Clínico San Carlos. Madrid. España
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La isquemia miocárdica es un fenómeno plurifactorial que produce un cambio hacia el metabolismo anaerobio en la célula muscular. Los cambios inducidos pueden ser reversibles en un primer momento antes de llegar al daño irreversible con muerte celular. El aumento en el aporte de oxígeno o la reducción de los requerimientos energéticos del miocardio protegen de la isquemia miocárdica. Desde el punto de vista fisiopatológico, el control y la reducción de la frecuencia cardiaca añadidos al restablecimiento del flujo coronario pueden ser la piedra angular en el tratamiento de esta afección.

Palabras clave:
Isquemia miocárdica

Myocardial ischemia is a multifactorial phenomenon that shifts muscle cells towards an anaerobic metabolism. At first, before irreversible damage leads to cell death, the resulting changes are reversible. Both an increase in oxygen supply and a reduction in myocardial energy demand can protect against myocardial ischemia. From a pathophysiological point of view, control of or a reduction in heart rate, combined with the re-establishment of coronary flow, can provide the cornerstone of treatment for this condition.

Key words:
Myocardial ischemia
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Revista Española de Cardiología

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