ISSN: 0300-8932 Factor de impacto 2023 7,2
Vol. 6. Núm. G.
Páginas 36G-45G (Septiembre 2006)

Tratamiento de las hiperlipemias en pacientes con riesgo cardiovascular elevado
Prevención y tratamiento del síndrome coronario agudo

Prevention and Treatment of Acute Coronary Syndrome

Antonio J. Domínguez FrancoMargarita Pérez CaravanteManuel F. Jiménez NavarroEduardo de Teresa Galván¿

Opciones

Los síndromes coronarios agudos (SCA) son la manifestación clínica final de un proceso inflamatorio crónico de la pared vascular puesto en marcha por diferentes agentes que causan daño en el endotelio. La rotura o la erosión de la placa aterosclerótica vulnerable provocan la trombosis y la aparición de los SCA. La respuesta inflamatoria local y sistémica desempeña un papel fundamental en la vulnerabilidad y la rotura de la placa. En el presente artículo revisaremos la fisiopatología, las técnicas disponibles para la detección de la placa vulnerable, el papel de las estatinas en el SCA (ensayos clínicos publicados) y las implicaciones terapéuticas para la prevención de las complicaciones trombóticas de la aterosclerosis.

Palabras clave

Síndrome coronario agudo
Inflamación
Placa vulnerable
Aterosclerosis
Trombosis
Estatinas
Prevención
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