Publish in this journal
Journal Information
Vol. 69. Issue 6.
Pages 631-632 (June 2016)
Vol. 69. Issue 6.
Pages 631-632 (June 2016)
Letter to the Editor
Full text access
Time of Pacemaker Implantation After Percutaneous Aortic Valve Replacement. Response
Momento del implante de un marcapasos tras el recambio valvular aórtico percutáneo. Respuesta
José López-Aguilera
Corresponding author

Corresponding author:
, José M. Segura, José Suárez de Lezo
Servicio de Cardiología, Hospital Universitario Reina Sofía, Córdoba, Spain
Related content
Rev Esp Cardiol. 2016;69:630-110.1016/j.rec.2016.01.026
Alfredo Renilla, José M. Rubín, César Morís
This item has received
Article information
Full Text
Download PDF
Full Text
To the Editor,

We appreciate the publication of the letter from Renilla et al concerning our article about the changes in cardiac conduction following implantation of a CoreValve prosthesis.1 After reading the letter carefully, we would like to make a few comments on their reflections.

It is true that this prosthesis has frequently been associated with the need for a pacemaker, especially when this percutaneous technique was starting to be introduced. One of the reasons is probably that pointed out by the authors: the lack of data on the time course of complete atrioventricular block secondary to valve implantation. During the early years of the technique, many of the indications for pacemaker insertion were due to the development of new conduction disturbances, other than complete atrioventricular block, with unknown natural courses. Although controversy remains to this day,2,3 in our experience, patients with new onset left bundle branch block after valve implantation are no more likely to need a pacemaker because of this acquired conduction disturbance than patients without this disorder. The course of patients who develop right bundle branch block after transcatheter aortic valve implantation appears to be different; in our series, this subgroup of patients seems to exhibit an early increase in the probability of needing a pacemaker.

As to setting an exact time limit to the causal relationship between implantation of the valved stent and the need for a permanent pacemaker, we agree with Renilla et al in that it is complicated. Although some authors establish a limit of 30 days, according to the latest European Society of Cardiology guidelines,4 if bradycardia is significant and does not resolve within an adequate period of observation after prosthesis implantation (established as 1 week), insertion of a permanent pacemaker is unavoidable. Regardless of this consideration, we cannot lose sight of the fact that these patients are very elderly and have a disease that affects the conduction tissue and impulse generation. Proof of this are the 2 patients (1.1%) who had recurrent syncopal episodes for whom we requested pacemaker implantation, although their atrioventricular conduction was intact, because late electrophysiological studies revealed sinus node dysfunction after 1 month and 20 months of follow-up, respectively.1

J. López-Aguilera, J.M. Segura, F. Mazuelos, J. Suárez de Lezo, S. Ojeda, M. Pan, et al.
Modificación de la conducción auriculoventricular tras el implante de prótesis aórtica CoreValve.
Rev Esp Cardiol., 69 (2016), pp. 28-36
P. Houthuizen, L.A. van Garsee, T.T. Poels, P. de Jaegere, R.M. van der Boon, B.M. Swinkels, et al.
Left bundle-branch block induced by transcatheter aortic valve implantation increases risk of death.
Circulation., 126 (2012), pp. 720-728
L. Testa, A. Latib, F. de Marco, M. de Carlo, M. Agnifili, R.A. Latini, et al.
Clinical impact of persistent left bundle-branch block after transcatheter aortic valve implantation with CoreValve Revalving System.
Circulation., 127 (2013), pp. 1300-1307
M. Brignole, A. Auricchio, G. Baron-Esquivias, P. Bordachar, G. Boriani, O.A. Breithardt, et al.
2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy. Developed in collaboration with the European Heart Rhythm Association (EHRA).
Eur Heart J., 34 (2013), pp. 2281-2329
Copyright © 2016. Sociedad Española de Cardiología
Revista Española de Cardiología (English Edition)

Subscribe to our newsletter

View newsletter history
Article options
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?