Publish in this journal
Journal Information
Vol. 72. Issue 3.
Pages 245 (March 2019)
Download PDF
More article options
Vol. 72. Issue 3.
Pages 245 (March 2019)
Image in cardiology
DOI: 10.1016/j.rec.2018.05.007
Full text access
Massive Myocardial Necrosis due to Churg-Strauss Syndrome
Necrosis miocárdica masiva por síndrome de Churg-Strauss
Eneko Barberíaa,b,
Corresponding author

Corresponding author:
, Inés Landína,b, Concepción Dasic
a Servicio de Patología Forense, Institut de Medicina Legal i Ciències Forenses de Catalunya, Tarragona, Spain
b Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Tarragona, Spain
c Servicio de Histopatología, Instituto Nacional de Toxicología y Ciencias Forenses, Barcelona, Spain
Article information
Full Text
Download PDF
Figures (3)
Show moreShow less
Full Text

Churg-Strauss syndrome has been described as a type of disseminated necrotizing vasculitis with extravascular granulomas that occurs in patients with asthma and eosinophilia. Several organs may be involved and its incidence is low. Cardiac complications can be varied and are associated with a worse prognosis.

We present the case of a 38-year-old Spanish man with a history of asthma and cannabis consumption. After several days of general malaise, weight loss, and asthenia, he had a cardiorespiratory arrest and died after advanced cardiopulmonary resuscitation. Forensic autopsy revealed, among other findings, pericarditis and pericardial effusion of a purulent appearance, cardiomegaly, and findings consistent with left ventricular and papillary muscle necrosis (Figure 1 and Figure 2). The provisional diagnosis was sudden cardiac death due to myocarditis.

Figure 1
Figure 2

Histopathology study showed necrotizing vasculitis with disseminated extravascular granulomas and hypereosinophilia, with involvement of several organs. From the cardiological point of view (Figure 3), a massive ongoing heart attack was detected with intracardiac thrombosis. Interstitial eosinophilic infiltrate and myocardial fiber necrosis (Figure 3A, hematoxylin-eosin × 40), necrotizing vasculitis with intraluminal thrombosis (Figure 3B, hematoxylin-eosin × 40), and presence of extravascular granulomas and giant cells (Figure 3C and D, arrow; hematoxylin-eosin × 40) were observed. The final diagnosis was death caused by massive myocardial necrosis due to Churg-Strauss syndrome.

Figure 3
Copyright © 2018. Sociedad Española de Cardiología
Revista Española de Cardiología (English Edition)

Subscribe to our newsletter

Article options
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?