Publish in this journal
Journal Information
Vol. 68. Issue 5.
Pages 437 (May 2015)
Download PDF
More article options
Vol. 68. Issue 5.
Pages 437 (May 2015)
Image in cardiology
Full text access
Optical Coherence Tomography in Thromboembolic Pulmonary Hypertension
Hallazgos por tomografía de coherencia óptica en la hipertensión pulmonar tromboembólica
Ángel Sánchez-Recaldea,
Corresponding author

Corresponding author:.
, Sergio Alcoleab, Juan José Ríos-Blancoc
a Servicio de Cardiología, Hospital Universitario La Paz, Madrid, Spain
b Servicio de Neumología, Hospital Universitario La Paz, Madrid, Spain
c Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, Spain
Article information
Full Text
Download PDF
Figures (1)
Additional material (2)
Full Text

Thromboembolic pulmonary hypertension is caused by thrombotic obstruction of the pulmonary artery tree after a thromboembolic event. If the thrombotic event does not resolve, fibrotic changes associated with vascular remodeling occur, leading to increased pulmonary resistance. An 80-year-old man was diagnosed with severe hypertension by echocardiography after signs and symptoms of acute pulmonary thromboembolism 2 years earlier. Cardiac catheterization found a pulmonary pressure of 80/30mmHg (mean, 47mmHg), with a resistance of 9 UW. Pulmonary angiography showed partial filling defects in both main pulmonary arteries. Optical coherence tomography is an imaging technique that allows the arterial wall to be visualized with microscopic resolution. It can be useful for studying certain arterial wall disorders in vivo. In the basal arterial segment of the inferior lobe (Figure A, arrows; video 1 of the supplementary material), optical coherence tomography showed intimal thickening in the adjacent distal region (Figure B), multiple fibrous tracts forming a honeycomb-like structure associated with recanalized thrombosis (Figures C-F, video 2 of the supplementary material), and recent proximal intimal thickening (Figure G). The 3-dimensional reconstruction shows a tangle of fibrous tracts (Figure H, asterisk) which, with the associated flow resistance, could partly explain the pulmonary hypertension. Optical coherence tomography could be the technique of choice for diagnosing distal thromboembolic pulmonary hypertension and guiding percutaneous intervention.

Copyright © 2014. Sociedad Española de Cardiología
Revista Española de Cardiología (English Edition)

Subscribe to our newsletter

Article options
Supplemental materials
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?